RESEARCH | Publications | Service/Teaching

Neuroscience Discipline

Center for Neurodegenerative Disease and Therapeutics

My research interests focus on studying the early neuronal pathology that develops in Alzheimer's disease (AD), long before the deposition of plaques and tangles, and cognitive decline. To accomplish this, I use transgenic mice engineered to express human gene mutations that cause the inheritable form of AD, as well as human neurons derived from AD patients. With these tools, I can examine within individual neurons and entire networks how AD mutations impair neuronal functioning and synaptic plasticity across various stages of the disease process, with the goal of finding ways to block or reverse these impairments. By the time memory loss occurs in humans, the damage to the brain is often too extensive to reverse. My previous studies show that specific calcium-mediated signaling pathways are highly dysregulated in AD, and over time, facilitate the formation of amyloid plaques and tangles, interfere with neuronal signaling processes that support learning and memory, and eventually kill the cell. We are pursuing novel therapeutic strategies designed to prevent these early pathogenic processes, preserve synapses, and prevent memory impairment. This approach targets mechanisms upstream of amyloid and tau pathology. To achieve these goals, I use innovative techniques to study real-time activity in living neurons from rodents and humans, such as in vitro electrophysiology combined with 2-photon and CCD imaging of calcium signals within cellular compartments. In addition, extracellular recording techniques, immunohistochemistry, molecular biology and behavioral approaches are also incorporated. With my collaborators, we are also formulating and testing novel target compounds that impede the progression of AD pathology at its earlier stages. By combining the study of basic disease mechanisms in mice and human cells in parallel with drug discovery and therapeutic applications, we hope to develop effective options to prevent AD.

Education

Washington and Lee University
BS Biology/Psychology Cum laude
Omicron Delta Kappa (National Leadership Honor Society)

Stony Brook University
MA BioPsychology (Advisor: Dr. Rex Wang, PhD)

New York University
PhD Center for Neural Science (Advisor: Dr. Joseph LeDoux, PhD, Henry and Lucy Moses Professor of Science)

Training

Post Doctoral Research Fellow (Mentor: Dr. George Aghajanian)
Yale University School of Medicine
Departments of Psychiatry and Pharmacology

Post Doctoral Research Fellow (Mentors: Dr. Frank LaFerla, Chancellor's Professor and Dean; Dr. Ian Parker, FRS, AAAS Fellow) University of California, Irvine
Department of Neurobiology and Behavior

Current Appointment

Professor, Neuroscience, Department of Foundational Sciences & Humanities
Director, Center for Neurodegenerative Disease and Therapeutics
The Chicago Medical School
无码群交 of Medicine and Science
Founder and CSO, NeuroLucent, Inc.

Affiliations/Memberships

RFUMS:
Center for Stem Cell and Regenerative Medicine
TBI-PTSD Working Group
Women in Medicine and Science - RFUMS Executive Council

Association of Anatomy, Cell Biology and Neurobiology Chairpersons
SmartHealth Biotech Accelerator, North Chicago, IL

Honors, Awards, and Lectureships

2003 Al Nichols Young Investigator Award, UC Irvine Institute for Brain Aging and Dementia Fund for Advanced
Research in Priority Areas: Calcium Signaling Workshop Fellowship Award (Chile)
2004 Full Scholarship Award, Optical Microscopy in the Biological Sciences Course (UT San Antonio)
Dorothy Dillon Eweson Lecturer on the Advances in Aging Research, American Foundation of Aging Research (AFAR)
2006 AFAR-NYAS-GE Healthcare NeuroImaging Prize for Junior Investigators
2007 AFAR Travel Award, Biomarkers in Alzheimer's Disease (New York, NY)
2008 Board of Trustees Award, RFUMS
2009 Outstanding Contributor Award/The Alzheimer's Research Forum
Best Biological Paper/Microscopy Society of America Award "Seeing the Brain in Action: How Multiphoton Imaging has Advanced our Understanding of Neuronal Function" (2008) Microsc. Microanal. 14, 482-491.
2011, 2012, 2018 Dorothy Dillon Eweson Lecturer on the Advances in Aging Research (AFAR)
2018 “Researchers to Know: Advancing Medicine” IL Science and Technology Coalition
2020 Morris L. Parker Award for Research, RFUMS

Scientific Advisory/Consulting/Service Roles

Councilor, Chicago Chapter of the Society for Neuroscience (2009-2011)
Alzheimer’s Research Trust, Expert Referee Panel (Great Britain) (2009-present)
Alzheimer’s Research Forum (2009-present)
Alumni in Residence Program, Washington and Lee University (2009-present)
Key Opinion Leader, The Campaign to Prevent Alzheimer’s Disease 2020 [PAD2020] (2010-present)
Italian Scientific Research Council (2010-present)
Society for Neuroscience Program Committee (2014-2017)
AFAR National Scientific Advisory Council (2014-present)
NIH Startup Business Challenge; Team Advisor, Illinois Institute of Technology (2014-present)
Neuroscience Program Committee, DePaul University (2014-present)
Advisory Board Member ‘CNS: Research to Clinic’ (2014-present)
Alzheimer’s Drug Discovery Foundation Scientific Review Board (2015-present)
Medical and Scientific Advisory Board, Alzheimer’s Association, IL Chapter (2015-present)

Research | Publications | Service/Teaching

Research

2005-present 无码群交 of Medicine and Science/The Chicago Medical School (Neuroscience DISCIPLINE, Department of foundational Sciences & Humanities)

My lab utilizes electrophysiological, multi-photon imaging, and molecular approaches to examine early mechanisms of neurodegenerative processes, particularly in aging, Alzheimer's disease, and traumatic brain injury. We have identified several aberrant calcium channels and related signaling pathways that appear to be drivers of pathogenic cycles in Alzheimer's and other neurological disorders. In particular, the ryanodine receptor is strongly implicated, and we have begun novel drug development strategies targeting this calcium channel as a means to develop therapeutic approaches to preserve cognitive function in aged and diseased brains.

Current Funding

NIH RF1AG0665628 Stutzmann, PI. 09/2020 - 08/2024 "Intracellular Organelle Deficits Driving Alzheimer’s disease"

NIH 1RF1NS114570-01 Stutzmann, Sub PD/PI. 08/2020 – 07/2024 "Calcium and the Pathophysiology of Neurodegenerative Disorders"

NIH 1RF1AG077103-01A1 Stutzmann, Co-PI. 02/2023- 01/2026 "Septhohippocamal Connectome Dysfunction in Down Syndrome Associated with Alzheimer’s Disease Pathophysiology"

NIH R01AG082135 Stutzmann, Co-I. 4/15/23 - 12/31 /27 "Sex-specific regulation of microRNAs in Alzheimer Disease"

NIH 1R21AG083638-01 Stutzmann, PI. 07/2023 – 06/2025 "Utilizing gene-level biomarkers of AD to identify pathophysiological mechanisms in human neurons"

2001-2005 University of California, Irvine (Department of Neurobiology and Behavior - Ian Parker and Frank LaFerla, PI's)

In vitro whole-cell electrophysiological recording, multi-photon imaging and molecular/transgenic studies examining mechanisms of neuronal calcium signaling, and mutations related to Alzheimer's disease and neurodegenerative diseases.

1999-2000 Yale University School of Medicine (Departments of Psychiatry and Pharmacology - George Aghajanian, PI)

In vitro sharp and whole cell electrophysiological recordings in cortical and hippocampal slices examining effects of serotonin and adenosine on neuronal activity in relation to psychosis and drugs of abuse.

1995-1999 New York University (W.M. Keck Foundation Laboratory of Neurobiology, Center for Neural Science - Joseph E. LeDoux, Henry and Lucy Moses, PI)

Intracellular and extracellular in vivo and in vitro electrophysiology, iontophoresis, and immunohistochemistry studies examining effects of serotonin and stress hormones on amygdala neurons.

1992-1994 SUNY at Stony Brook (Department of Psychiatry - Rex Wang, PI)

Electrophysiology, in vivo single unit recording, iontophoresis and behavior studies examining serotonergic and dopaminergic involvement in psychosis and drugs of abuse.

Lab Members

	Daniel Steinbrenner, PhD   Senior Research Fellow
	Renuka Ramachandra, PhD  Senior Research Fellow
	Sarah Mustaly-Kalimi, PhD  Research Fellow
	Nikki Barrington, MD/PhD graduate student
	Elise Webber, PhD graduate student
	Wacey Gallegos, PhD graduate student
	Anait Nalbandyan  Undergraduate researcher (Lake Forest College)

Research | Publications | Service/Teaching

Recent Publications

Peer-Reviewed Publications

Bazarek SF, Thaqi M, King P, Mehta AR, Patel R, Briggs CA, Reisenbigler E, Yousey JE, Miller EA, Stutzmann GE, Marr RA, Peterson DA. Engineered neurogenesis in naïve adult rat cortex by Ngn2-mediated neuronal reprogramming of resident oligodendrocyte progenitor cells. Front Neurosci. 2023 Aug 17;17:1237176. doi: 10.3389/fnins.2023.1237176. PMID: ; PMCID: PMC10471311.

Webber EK, Fivaz M, Stutzmann GE, Griffioen G. Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond. Alzheimers Dement. 2023 Aug;19(8):3701-3717. doi: 10.1002/alz.13065. Epub 2023 May 3. PMID: ; PMCID: PMC10490830.

Rozenfeld M, Azoulay IS, Ben Kasus Nissim T, Stavsky A, Melamed M, Stutzmann G, Hershfinkel M, Kofman O, Sekler I. Essential role of the mitochondrial Na+/Ca2+ exchanger NCLX in mediating PDE2-dependent neuronal survival and learning. Cell Rep. 2022 Dec 6;41(10):111772. doi: 10.1016/j.celrep.2022.111772. PMID: .

Wiseman AL, Briggs CA, Peritt A, Kapecki N, Peterson DA, Shim SS, Stutzmann GE. Lithium Provides Broad Therapeutic Benefits in an Alzheimer's Disease Mouse Model. J Alzheimers Dis. 2023;91(1):273-290. doi: 10.3233/JAD-220758. PMID: .

Mustaly-Kalimi S, Gallegos W, Marr RA, Gilman-Sachs A, Peterson DA, Sekler I, Stutzmann GE. Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2211999119. doi: 10.1073/pnas.2211999119. Epub 2022 Nov 28. PMID: ; PMCID: PMC9894236.

Stoler O, Stavsky A, Khrapunsky Y, Melamed I, Stutzmann G, Gitler D, Sekler I, Fleidervish I. Frequency- and spike-timing-dependent mitochondrial Ca2+ signaling regulates the metabolic rate and synaptic efficacy in cortical neurons. Elife. 2022 Feb 22;11:e74606. doi: 10.7554/eLife.74606. PMID: ; PMCID: PMC8906805.

Alldred MJ, Lee SH, Stutzmann GE, Ginsberg SD. Oxidative Phosphorylation Is Dysregulated Within the Basocortical Circuit in a 6-month old Mouse Model of Down Syndrome and Alzheimer's Disease. Front Aging Neurosci. 2021 Aug 19;13:707950. doi: 10.3389/fnagi.2021.707950. PMID: ; PMCID: PMC8417045.

Christian DT, Stefanik MT, Bean LA, Loweth JA, Wunsch AM, Funke JR, Briggs CA, Lyons J, Neal D, Milovanovic M, D'Souza GX, Stutzmann GE, Nicholson DA, Tseng KY, Wolf ME. GluN3-Containing NMDA Receptors in the Rat Nucleus Accumbens Core Contribute to Incubation of Cocaine Craving. J Neurosci. 2021 Sep 29;41(39):8262-8277. doi: 10.1523/JNEUROSCI.0406-21.2021. Epub 2021 Aug 19. PMID: ; PMCID: PMC8482856.

McDaid J, Briggs CA, Barrington NM, Peterson DA, Kozlowski DA, Stutzmann GE. Sustained Hippocampal Synaptic Pathophysiology Following Single and Repeated Closed-Head Concussive Impacts. Front Cell Neurosci. 2021 Mar 31;15:652721. doi: 10.3389/fncel.2021.652721. PMID: ; PMCID: PMC8044326.

Stutzmann GE. RyR2 calcium channels in the spotlight-I'm ready for my close up, Dr. Alzheimer! Cell Calcium. 2021 Mar;94:102342. doi: 10.1016/j.ceca.2020.102342. Epub 2021 Jan 2. PMID: .

McDaid J, Mustaly-Kalimi S, Stutzmann GE. Ca²⁺ Dyshomeostasis Disrupts Neuronal and Synaptic Function in Alzheimer's Disease. Cells. 2020 Dec 10;9(12):2655. doi: 10.3390/cells9122655. PMID: ; PMCID: PMC7763805.

Schrank S, McDaid J, Briggs CA, Mustaly-Kalimi S, Brinks D, Houcek A, Singer O, Bottero V, Marr RA, Stutzmann GE. (2020) Human induced neurons from PS1 mutant patients model early aspects of Alzheimer’s disease pathology. International Journal of Molecular Sciences. 21(3). PMID:

Chakroborty S, Manfredsson FP, Dec AM, Campbell PW, Stutzmann GE, Beaumont V, West AR. (2020) Phosphodiesterase 9A inhibition facilitates corticostriatal transmission in wild-type and transgenic rats that model Huntington’s disease. Frontiers in Neuroscience. 14:466. PMID

Chakroborty S, Hill E. Christian DT, Helfrich R, Riley S, Kapecki N, Mustaly S, Seiler FA, Schneider C, Peterson DA, West AR, Vertel BM, Frost WN, Stutzmann GE. (2019) Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer’s disease. Molecular Neurodegeneration, 22;14(1):7. PMID:

Padovan-Neto FE, Jurkowski L, Murray C, Stutzmann GE, Kwan M, Ghavami A, Beaumont V, Park LC, West AR. (2018) Age- and sex-related changes in cortical and striatal nitric oxide synthase in the Q175 mouse model of Huntington’s disease. Nitric Oxide, 83:40-50. PMID:

Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR (2017) Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer’s disease-like pathologies and cognitive deficits. Acta Neuropathol, 134(5):749-767.  doi:   PMID: 

Jamnia N, Urban JH, Stutzmann GE, Chiren S, Reisenbigler E, Marr R, Peterson DA, Kozlowski DA (2016) A clinically relevant closed-head model of single and repeat concussive injury in the adult rat using a controlled cortical impact device. J Neurotrauma, 34(7):1351-1363.  doi:   PMID: 

Christian DT, Wang X, Chen EL, Sehgal LK, Ghassemlou MN, Miao JJ, Estepanian D, Araghi CH, Stutzmann GE, Wolf ME (2016) Dynamic Alterations of Rat Nucleus Accumbens Dendritic Spines over two Months of Abstinence from Extended-Access Cocaine Self-Administration. Neuropsychopharmacology, 42(3):748-756.  doi:   PMID: 

Anthony J. Hinrich, Francine M. Jodelka, Jennifer L. Chang, Daniella Brutman, Angela Bruno, Clark A. Briggs, Bryan D. James, Grace E. Stutzmann, et al. (2016) Therapeutic Correction of ApoER2 Splicing in Alzheimer’s Disease Mice Using Antisense Oligonucleotides. EMBO Molecular Medicine, 8(4):328-45.  doi:   PMID: 

Chakroborty S, Kim J, Schneider C, West A, Stutzmann GE (2015) Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer’s disease mice. Journal of Neuroscience, 35(17), 6893-902.  doi:    PMID:

Briggs CA, Schneider C, Richardson JC, Stutzmann GE (2013) Beta amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice. Neurobiology of Aging, 34(6):1632-43.  doi:   PMID: 

Chakroborty S, Briggs C, Miller MB, Goussakov I, Schneider C, Kim J, Wicks J, Richardson J, Conklin V, Cameransi B, Stutzmann GE (2012) Stabilizing ER calcium channel function as an early prevention strategy for Alzheimer’s disease. PLoS One, 7(12): e52056.  PMID: 

Ferrario CR, Goussakov I, Stutzmann GE, Wolf ME. (2012) Withdrawal from cocaine self-administration alters NMDA receptor-mediated Ca²⁺ entry in nucleus accumbens dendritic spines. PLOS One, 7(8): e40898.  doi:   PMID: 

Chakroborty S, Kim J, Schneider C, Jacobson C, Molgó J, Stutzmann GE. (2012a) Early pre- and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice Journal of Neuroscience, 32(24):8341-53.  doi:   PMID: 

Stutzmann GE (2011) Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer’s Disease. Neurobiology of Aging 33(5):1001.e1-6.  doi:   PMID: 

Goussakov I, Chakroborty S, Stutzmann GE (2011) Generation of dendritic Ca2+ oscillations as a consequence of altered ryanodine receptor function in AD neurons. Channels, 5(1):9-13.  doi:   PMID: 

Perez MF, Ford K, Goussakov I, Stutzmann GE, Hu XT (2011) Repeated Cocaine Exposure Decreases Dopamine D2-Like Receptor Modulation of Ca2+ Homeostasis in Rat Nucleus Accumbens Neurons. Synapse, 65(2):168-180.  doi:   PMID: 

Goussakov I, Miller M, Stutzmann GE (2010) NMDA-mediated Ca2+ influx drives ryanodine receptor activation in dendrites of young Alzheimer's disease mice. Journal of Neuroscience, 30(36):12128-37.  doi:   PMID: 

Chakroborty S, Goussakov I, Miller MB, Stutzmann GE (2009) Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice. Journal of Neuroscience, 29: 9458-9470.  doi:   PMID:   *Faculty of 1000 Recommended Reading Award

Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, LaFerla F (2007) Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer mouse models. Annals of the New York Academy of Science, 1097: 265-277.  doi:   PMID:

Stutzmann GE, Smith I, Caccamo A, Oddo S, LaFerla FM, Parker I (2006) Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult and aged Alzheimer’s disease mice. Journal of Neuroscience, 26(20) 5180-5189.  doi:   PMID: 

Stutzmann GE, Caccamo A, LaFerla FM, Parker I (2004) Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. Journal of Neuroscience, 24(2) 508-513.  doi:   PMID: 

Stutzmann GE, LaFerla FM, Parker I (2003) Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate. Journal of Neuroscience, 23(3):758-65.  doi:   PMID: 

Marchant J, Stutzmann GE, Leissring M, LaFerla F, Parker I (2001) Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. Nature Biotechnology, 19:645-649.  doi:   PMID: 

Stutzmann GE, Marek GJ, Aghajanian GK (2001) Adenosine preferentially suppresses serotonin2A-receptor enhanced EPSC’s in layer V neurons of the medial prefrontal cortex. Neuroscience, 105:55-69.  doi:   PMID: 

Stutzmann GE, LeDoux JE (1999) GABAergic antagonists block the inhibitory effects of serotonin in the lateral amygdala: a mechanism for modulation of sensory inputs related to fear conditioning. Journal of Neuroscience, 19(11):1-4.  doi:   PMID: 

Stutzmann GE, McEwen BS, LeDoux JE (1998) Serotonin modulation of sensory inputs to the lateral amygdala: dependency on corticosterone. Journal of Neuroscience, 18(22):9529-38.  doi:   PMID: 

Li XF, Stutzmann GE, LeDoux JE (1996) Convergent but temporally separated inputs to lateral amygdala neurons from the auditory thalamus and auditory cortex use different postsynaptic receptors: in vivo intracellular and extracellular recordings in fear conditioning pathways. Learning and Memory, 3(2-3):229-42.  doi:   PMID: 

Minabe Y, Emori K, Toor A, Stutzmann GE, Ashby CR (1996) The effect of the acute and chronic administration of CP 96,345, a selective neurokinin1 receptor antagonist, on midbrain dopamine neurons in the rat: a single unit, extracellular recording study. Synapse, 22(1):35-45.  doi:   PMID: 

Invited Reviews

McDaid J, Mustaly-Kalimi S, Stutzmann GE (2020) Ca²⁺ Dyshomeostasis Disrupts Neuronal and Synaptic Function in Alzheimer's Disease. Cells. 10;9(12):2655.

Stutzmann GE (2021) RyR2 calcium channels in the spotlight-I'm ready for my close up, Dr. Alzheimer! Cell Calcium. 94:102342. Epub ahead of print. PMID: 33444912.

Mustaly-Kalimi S, Littlefield AM, Stutzmann GE. (2018) Calcium Signaling Deficits in Glia and Autophagic Pathways Contributing to Neurodegenerative Disease. Antioxid Redox Signal.  [Epub ahead of print] doi: PMID:

Alzheimer’s Association Calcium Hypothesis Workgroup (2017) Calcium Hypothesis of Alzheimer's disease and brain aging: A framework for integrating new evidence into a comprehensive theory of pathogenesis. Alzheimers Dement. 13(2):178-182.e17. doi: PMID:

Briggs CA, Chakroborty S, Stutzmann GE (2017) Emerging pathways driving early synaptic pathology in Alzheimer’s disease. Biochem Biophys Res Commun. 483(4):988-997. doi: PMID:

Shim, SS, Stutzmann GE (2016) Inhibition of glycogen synthase kinase-3: an emerging target in the treatment of traumatic brain injury. Journal of Neurotrauma. 33(23):2065-2076. doi: PMID:

Chakroborty S, Stutzmann GE (2014) Calcium channelopathies and Alzheimer's disease: insight into therapeutic success and failures. Eur J Pharmacol. 739:83-95. doi: PMID:

Chakroborty S, Stutzmann GE (2011) Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction. Sci China Life Sci. 54(8):752-62. doi: PMID:

Stutzmann GE, Mattson MP (2011) Endoplasmic reticulum Ca2+ handling in excitable cells in health and disease. Pharmacol Rev. 63(3):700-27. doi: PMID:

Demuro A, Parker I, Stutzmann GE (2010) Calcium signaling and amyloid toxicity in Alzheimer's disease. J Biol Chem. 285(17):12463-8. doi: PMID:

Stutzmann GE (2008) Seeing the brain in action: how multiphoton imaging has advanced our understanding of neuronal function. Microsc Microanal.  14(6):482-91. *Best Biological Paper Award. doi: PMID:

Stutzmann GE (2007) The pathogenesis of Alzheimer disease: Is it a lifelong ‘calciumopathy’? Neuroscientist, 13(5):546-59. doi: PMID:

Stutzmann GE (2005) Calcium dysregulation, IP3, and Alzheimer’s disease. Neuroscientist, 11(2):110-5. doi: PMID:

Stutzmann GE, Parker I (2005) Dynamic multi-photon imaging: a live view from cells to systems. Physiology, 20:15-21. doi: PMID:

Research | Publications | Service/Teaching

Service/Teaching

Service

University Service – Leadership Roles (RFUMS)

2009-2011	Academic Assembly, Secretary
2011-2013	Academic Assembly, Deputy Speaker
2013-2015	Academic Assembly, Speaker
2009-present	Academic Assembly Advisory Committee Member

University Service – Committee Membership (RFUMS)

2006-present	Molecular & Cellular Sciences Seminar Series Committee
2007-2013	University Senate, Member
2007-2010	Library Steering Committee
2008-2009	Student Learning Center Steering Committee
2008-2013	University Environmental Sustainability Committee
2008-present	Graduate Oversight Committee
2009-present	Bridging Grant Research Review Committee
2010	Chicago Medical School Dean Search Committee
2010-2011	University Research Summit, Participant
2010-2015	University Tenure and Credentials Committee
2012-2015	Institutional Biosafety Committee
2012-present	Neurodegeneration and Repair Consortium, Founder
2013-2014	CMS Admissions Task Force
2013-2014	CMS Strategic Planning Task Force
2013-2014	Academic Advancement Council
2013-2014	LCME Task Force member, IS-13
2013-present	LCME Task Force member, IS-4
2014-present	LCME Task Force member, ED-25
2014	Faculty Search Committee, Cellular and Molecular Pharmacology
2014-2015	Faculty Search Committee, College of Pharmacy
2015	Task Force on Faculty Development and Work Load Models
2015	CQL-LCME Task Force Committee
2015-present	Student Evaluation and Promotion Committee

Neuroscience Service

2009-2010	Co-Chair, Performance Review Committee for Annual Neuroscience Dept. Chair Review
2011-2012	Chair, Performance Review Committee for Annual Neuroscience Dept. Chair Review

Teaching

RFUMS Chicago Medical School

Medical Neuroscience, Lecturer (2006-2018)
Essentials of Clinical Reasoning (2012-present)
Clinical Epidemiology (2013-present)
Clinical Genetics (2012-2014)
Introduction to Bioethics and Health Law (2012)

RFUMS IGPBS Graduate Program

Neurophysiology, Course Director (2008-present)
Molecular and Cell Biology II (2009-present)
Neuroscience Course (2010-present)
Systems (2014-present)
Brain Frontiers, Lecturer (2007)
Neuronal Signaling (2012)